Additive Benefit of Guideline-Directed Medical Therapies at Discharge in Reducing 30-Day Readmissions in Heart Failure.

ABSTRACT:

Background

Hospitalization-related costs for heart failure (HF) are a major contributor to the overall health care expenditure in the United States. Despite recommendations, guideline-directed medical therapy (GDMT) is underutilized at discharge in eligible patients, likely contributing to high readmission rates. Describing the effect of GDMT use at discharge may better inform institutions on the value of implementing focused therapy initiatives.

Objectives

This study aimed to examine the association between the number of active GDMT prescriptions at discharge and 30-day readmissions.

Methods

This retrospective cohort study analyzed 2,121 index hospitalizations for HF across 5 institutions from February 1, 2021, to October 31, 2024. Patients included were adults with

SUBMITTER: Willeford A 

PROVIDER: S-EPMC12721035 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature