Life Purpose Lowers Risk for Cognitive Impairment in a United States Population-Based Cohort.

ABSTRACT:

Objective

We investigated whether sense of purpose in life (PiL) is associated with a lower risk for and delayed onset of developing cognitive impairment in a diverse US population-based cohort.

Methods

Participants from the Health and Retirement Study aged 45 or older with normal cognitive performance at baseline and ≥ 2 subsequent objective cognitive assessments were included. Cognitive performance was objectively assessed biennially using the modified Telephone Interview for Cognitive Status (mTICS). Cognitive impairment was defined as having two consecutive visits with mTICS scores below a psychometrically validated threshold consistent with mild cognitive impairment or dementia. PiL was assessed at baseline using a seven-item questionnaire. Cox Proportional Hazards was

SUBMITTER: Howard NC 

PROVIDER: S-EPMC12721275 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature