The bilirubin-to-albumin ratio as a potential prognostic biomarker for all-cause mortality in patients with acute decompensated cirrhosis: A prospective study.

ABSTRACT:

Background

Acute decompensation (AD) of liver cirrhosis is a life-threatening condition with high mortality and a significant healthcare burden. Although various prognostic models are available, their complexity often limits their practical utility in clinical settings. The bilirubin-to-albumin (B/A) ratio has emerged as a potential biomarker for critically ill patients. Despite its simplicity, the prognostic value of the B/A ratio in patients with AD remains uncertain.

Methods

This two-center, prospective observational study screened 748 participants. After follow-up and application of the exclusion criteria, 279 patients with AD were included in the final analysis. The B/A ratio was evaluated for its association with 30-day, 90-day, and 180-day mortality.

Results

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SUBMITTER: Viet Quang Nguyen H 

PROVIDER: S-EPMC12721523 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature