Green synthesized silver nanoparticles from Moringa: Potential for preventative treatment of SARS-CoV-2 contaminated water.

ABSTRACT: Biogenic silver nanoparticles have been reported as good antimicrobial candidates. In this study, we synthesized and characterized silver nanoparticles using aqueous leaf extracts of Moringa oleifera (AgNPmo) and investigated their antimicrobial and antiviral activities. The AgNPmo demonstrated antibacterial activity against Pseudomonas aeruginosa and Staphylococcus aureus, with concentration-dependent zones of inhibition ranging from 6.5-15.5 mm and 0-7 mm, respectively. Cytotoxicity was assessed on Vero cells using a CCK-8 assay, which revealed an IC50 value of 38 µg/ml, indicating relatively low toxicity at effective concentrations. The antiviral activity against SARS-CoV-2 was confirmed using quantitative RT-PCR: AgNPmo exposure led to a time- and dose-dependent increase in Ct values f

SUBMITTER: Ebunoluwa OB 

PROVIDER: S-EPMC12721540 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature