Longitudinal patterns and group heterogeneity of depressive symptoms during menopausal transition in middle-aged Korean women.

ABSTRACT:

Aims

While depressive symptoms are common during menopausal transition, the relationship between the two remains unclear. Therefore, this study aimed to examine the longitudinal changes in depressive symptoms among middle-aged Korean women and identify those with elevated and worsening symptoms during this period.

Methods

A total of 1,178 participants who underwent comprehensive health examinations at Kangbuk Samsung Hospital in Korea were followed for a median of 10.8 years (IQR, 9.2-11.6; maximum, 12.7), including all women who reached natural menopause during follow-up, with only data prior to HRT initiation included. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression Scale (CES-D), and menopausal stages were classified according to th

SUBMITTER: Jang Y 

PROVIDER: S-EPMC12721986 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature