Transition from depression-free to death in late life: characteristics of bidirectional transitions in depression symptoms.

ABSTRACT:

Aims

Depression among middle-aged and older adults is a critical public health priority. Clarifying the dynamic evolution of depression is essential for establishing prevention and intervention strategies; however, relevant research is limited. The aim of this study was to elucidate the transition patterns underlying different depressive symptoms (DS) states.

Methods

Data from the China Health and Retirement Longitudinal Study were utilised in this study, which included participants aged ≥45 years with multiple DS assessments via the Center for Epidemiological Studies Depression Scale. Multi-state Markov models were employed to estimate transition probabilities and intensities between DS states, the total length of stay and mean sojourn time in each state and the hazard rati

SUBMITTER: Cui X 

PROVIDER: S-EPMC12722190 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature