Genomic structure and selection history across Angus populations worldwide: insights from ROH, selection mapping, and functional analyses.

ABSTRACT: Angus cattle, originally from Scotland, have been selectively bred for over 400 years, making them one of the most prominent beef breeds globally. Known for their adaptability, natural polled traits, and high-quality beef, Angus cattle have been intensively selected for growth, body size, and feed efficiency. This study investigates the genetic diversity, selection history, and key genomic regions across five Angus populations from the USA, Canada, Australia, Brazil, and Red Angus of America. Genomic data from 71,283 animals born between 1961 and 2024 were analyzed using Principal Component Analysis (PCA), phylogenetic tree construction, and Runs of Homozygosity (ROH), with the Generation Proxy Selection Mapping (GPSM) approach used to assess selection history. Functional annotation identi

SUBMITTER: Mulim HA 

PROVIDER: S-EPMC12722264 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature