Clinical and implementation outcomes of an antimicrobial stewardship intervention for rapid blood culture diagnostics.

ABSTRACT:

Objective

To evaluate the clinical and implementation outcomes of an antimicrobial stewardship program (ASP) intervention to improve antibiotic therapy for a rapid diagnostic test (RDT) for bloodstream infections (BSIs).

Design

Retrospective pre and postintervention study.

Setting

Single pediatric tertiary center from August 2022 to May 2024.

Participants

Patients presenting with a positive blood culture accompanied by the Verigene (VG) Gram-positive Blood Culture Nucleic Acid (BC-GP) assay. Implementation outcomes surveys were completed by infectious diseases (ID) clinicians and non-ID clinicians.

Methods

We implemented a 24 hours a day, 7 days a week (24/7) ASP intervention to improve response to BC-GP assay results. The primary clinical end point was

SUBMITTER: Abdelnour M 

PROVIDER: S-EPMC12722554 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature