Association between 24-h time-use composition and brain age: The IGNITE study.

ABSTRACT:

Introduction

The relationships between 24-h time-use composition (i.e., sleep, sedentary behavior, light physical activity, and moderate-to-vigorous physical activity [MVPA]) and brain morphology in older adulthood remain poorly understood. We examined associations between 24-h time-use composition and brain age using compositional data analysis, predicting that 24-h time use would be associated with brain age and that a greater amount of time engaged in MVPA would drive associations with younger brain age.

Methods

Baseline data from the Investigating Gains in Neurocognition in an Intervention Trial of Exercise (IGNITE; n = 648) were analyzed. Brain age was estimated using T1-weighted magnetic resonance imaging data. Time-use composition was derived from wrist-worn tr

SUBMITTER: Collins AM 

PROVIDER: S-EPMC12722602 | biostudies-literature | 2025 Oct-Dec

REPOSITORIES: biostudies-literature