The fru gene specifies male cooperative behaviors in honeybee colonies.

ABSTRACT: Conspecific individuals can benefit from behavioral interactions, but whether cooperative behaviors require dedicated control in the nervous system is poorly understood. We examine the genetics underlying obligate cooperative male behaviors in honeybee colonies (Apis mellifera) that are deeply hardwired. We screened for transcription factor genes and found that only the fruitless (fru) BTB zinc-finger gene was restricted to expression in males and in the nervous system. Reporter coexpression revealed Fru-positive neuronal cell populations that are involved in processing and integrating sensory information. Computer-assisted behavioral tracking of male bees with loss-of-function mutations in experimental colonies revealed that fru is specifically required for the rate and/or duration of soc

SUBMITTER: Kohnen S 

PROVIDER: S-EPMC12722765 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature