The cerebellar-related cognitive function is sensitive to aging: implications for early detection.

ABSTRACT:

Background

Accumulating evidence demonstrated that the cerebellum contributes to a wide range of sensorimotor and cognitive functions. However, the relationship between cerebellar function and cognitive abilities in normal aging populations remains unclear.

Methods

The present cross-sectional study tested cerebellar-related cognitive changes across middle to late adulthood using the Cerebellar Cognitive Affective Syndrome (CCAS) scale and a perceptual serial reaction time (SRT) task. Participants were divided into three groups: early-middle-aged adults (N = 18, 30-45 years), late-middle-aged adults (N = 19, 46-57 years), and older adults (N = 18, 60-78 years).

Results

Although all participants were identified as cognitively healthy by the Mini-Men

SUBMITTER: Ma Q 

PROVIDER: S-EPMC12722794 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature