Effect of psyllium husk on low anterior resection syndrome after rectal cancer surgery-a pilot prospective cohort study.

ABSTRACT:

Introduction

Low anterior resection syndrome (LARS) is a frequent, undesired consequence of rectal cancer surgery. Psyllium husk has been suggested as a nutritional supplement in the management of LARS, but without trial-based evidence of its effect. In preparation of a randomized clinical trial, this pilot study aimed to estimate the effect of Psyllium husk in patients with LARS, determining the treatment duration required to observe the effect and assess patient compliance.

Methods

This single arm phase II study included patients with LARS score >20 ten months or more after rectal resection. Patients who consented to participate were given 3.66 g Psyllium husk fiber twice daily for 56 days. The primary endpoint was severity of bowel dysfunction using the LARS score. The se

SUBMITTER: Holte SS 

PROVIDER: S-EPMC12722911 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature