Impact of implementing a pediatric early warning system on outcomes in hematopoietic stem cell transplant units in South America and Europe.

ABSTRACT:

Background/aim

Escala de Valoración de Alerta Temprana (EVAT) is a Spanish-language Pediatric Early Warning Score (PEWS) validated to predict the need for unplanned intensive care unit (ICU) transfer in hospitalized children with cancer. We assess the effect of PEWS implementation on hospitalized children undergoing hematopoietic stem cell transplantation (HSCT) in variable-resource centers in South America and Europe.

Methods

We analyzed data from a prospective registry of clinical deterioration events (CDE), defined as an unplanned ICU transfer, ICU-level intervention on the ward, ward cardiopulmonary arrest, or deterioration to death, among hospitals implementing PEWS. We included CDE occurring in patients under age 19 hospitalized in an HSCT unit between April 2017 and J

SUBMITTER: Quijano-Lievano ML 

PROVIDER: S-EPMC12722999 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature