Emerging technologies for monitoring breast cancer response to neoadjuvant chemotherapy: a systematic scoping review.

ABSTRACT:

Introduction

Neoadjuvant chemotherapy (NACT) is increasingly used in early breast cancer treatment and responses are highly variable. Accurate monitoring of tumour response is crucial for enabling precise surgical de-escalation, yet current methods are inadequate. This systematic scoping review explores emerging technologies for predicting, monitoring, and diagnosing pre-operative breast cancer response to NACT.

Methods

A search of Embase, Medline, PubMed, and Cochrane databases was conducted until January 26, 2024. Studies investigating ability to detect tumour response during or after NACT, and prior to surgery, were included, and placed into 12 technology categories. Those investigating novel technologies were further categorised by Technology Readiness Level.

Results<

SUBMITTER: Wright GC 

PROVIDER: S-EPMC12723055 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature