Visceral Adiposity and Inflammation Index as Predictors of Stroke Risk in Middle and Older Age: A Cohort Study Across Blood Pressure Groups.

ABSTRACT:

Objective

The visceral adiposity and inflammation index (VAII) is a composite index that combines the visceral adiposity index (VAI) and high-sensitivity C-reactive protein (hs-CRP), both of which are associated with stroke risk. This study aimed to investigate the association between VAII and stroke risk, with a particular focus on different blood pressure (BP) statuses, sexes, and age groups.

Methods

Data from 8883 participants in the China Health and Retirement Longitudinal Study were analyzed. VAII levels were categorized into quartiles, and stroke incidence was assessed. Restricted cubic spline analysis was used to assess the association between VAII and stroke risk on the basis of sex, age, and BP status. Sensitivity analyses, including complete-case analysis, multiple

SUBMITTER: Luwen H 

PROVIDER: S-EPMC12723208 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature