Development of a Novel Rotor Design for Counter-Current Centrifugal Extraction Based on Computational Fluid Dynamics Simulations.

ABSTRACT: This study introduces an innovative method for continuous multistage liquid-liquid extraction. Addressing challenges like coalescence and settling times that limit efficiency makes centrifugal partition extraction a promising technique for continuous product separation. It combines the benefits of a mixer-settler cascade with centrifugal extractors in one compact apparatus. The working principle is based on centrifugal partition chromatography, where two immiscible liquid phases are contacted inside a rotor, one serving as the mobile phase and the other as the stationary phase. In centrifugal partition extraction, both phases are mobile. The rotating apparatus allows dispersion and reduces settling time compared with static settlers, with its 300 times higher acceleration. To overcome cons

SUBMITTER: Volpert S 

PROVIDER: S-EPMC12723355 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature