2D Assemblies Based on a Tetraphenylethylene D,L-Cyclic Peptide Scaffold.

ABSTRACT: Two dimensional (2D) materials and aggregation-induced emission (AIE) fluorophores have recently gained attention due to their unique properties and application potential. However, the combination of AIE probes into 2D self-assembled systems under nanometric control remains elusive due to the sensitivity of supramolecular assemblies to subtle changes in the monomer structure. Herein, we present a new scaffold based on four nanotube-forming cyclic peptide (CP) units attached to a tetraphenylethene (TPE) core whose pH-dependent self-assembly results in light-emitting 2D nanosheets. An oxime bond connection was exploited to synthesize a discrete library of tetrakis-(cyclopeptide) tetraphenylethene monomers that self-assemble into 2D macrotubular nanoarrays under the suitable external stimulus

SUBMITTER: Bayon-Fernandez A 

PROVIDER: S-EPMC12723453 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature