Prognosis of increasing percentages of lesional body surface area in early stage mycosis fungoides.

ABSTRACT:

Background

Early-stage mycosis fungoides (MF) is often an indolent disease with a favourable prognosis, though 25% progress to advanced stages. Patients with ≥10% body surface area (BSA) involvement have a worse prognosis than those with <10%, but the impact of other BSA levels remains unclear.

Objectives

This study aimed to determine whether additional BSA cut-off points higher than 10% provide additional prognostic information.

Methods

This study included 401 patients with early-stage MF of the Leiden University Medical Centre and a validation cohort of 602 patients from the PROCLIPI database. Different percentages of lesional BSA were analysed both in the total groups and in subgroups of patients with only patch-stage disease or with patch-plaques-stage disease, an

SUBMITTER: Kersten JM 

PROVIDER: S-EPMC12723569 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature