Multi-omics and high-spatial-resolution omics: deciphering complexity in neurological disorders.

ABSTRACT:

Background

The world has witnessed a steady rise in neurological diseases, which represent a heterogeneous group of disorders characterized by complex pathogenesis involving disruptions at multiple molecular levels, including genomic, transcriptomic, proteomic, and metabolomic levels. These disorders, often caused by genetic mutations, metabolic imbalances, immune dysregulation, and environmental factors, pose significant challenges to global public health due to their high prevalence, mortality, and disability burden.

Results

The advent of high-throughput technologies, such as next-generation sequencing and mass spectrometry, has provided valuable insights into the underlying mechanisms of disease, especially the development of multi- and high-spatial-resolution omics techn

SUBMITTER: Liu X 

PROVIDER: S-EPMC12723665 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature