A NASSS framework-guided systematic review and exploratory modelling of digital health interventions for polypharmacy management in older adults.

ABSTRACT:

Background

Polypharmacy is a growing challenge in older adults with multimorbidity, increasing the risk of adverse drug events, hospital admissions, and healthcare utilisation. Technology-supported interventions, such as clinical decision support systems (CDSS) and digital deprescribing tools, offer new opportunities to optimize medication use. However, adoption and sustainability remain variable across healthcare settings. The Non-adoption, Abandonment, Scale-up, Spread, and Sustainability (NASSS) framework offers a valuable lens to evaluate complex digital health interventions targeting medication optimization in older adults.

Objective

This review systematically examines the adoption, scale-up, and sustainability of technology-supported medicines optimization intervention

SUBMITTER: Vamadevan A 

PROVIDER: S-EPMC12723875 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature