Outcome measures for irritable bowel syndrome: a scoping review.

ABSTRACT:

Background

Irritable bowel syndrome (IBS) is one of the most common gut-brain interaction disorders. Most current IBS randomized controlled trials (RCTs) do not justify their choice of outcomes, and inappropriate outcome selection may obscure efficacy evaluation.

Objective

In this study, we systematically organize outcome-related information from IBS RCTs, encompassing two key components: categorizing outcomes into distinct domains, and summarizing the corresponding outcome measurement instruments for each domain. We also classify these outcome measures based on drug therapeutic mechanisms, IBS subtypes, and the research aims of RCTs, providing a reference basis for the comprehensive and accurate selection of outcome measures for IBS RCTs.

Search strategy

We developed

SUBMITTER: Mo JH 

PROVIDER: S-EPMC12723903 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature