Polymersome-based nanomedicine for combined cancer therapy.

ABSTRACT: Cancer is a complex disease characterized by uncontrolled cell growth and spread, often resulting in metastasis. The use of combination therapy, which involves the simultaneous application of two or more treatment methods, aims to enhance effectiveness and improve patient outcomes. This approach can enhance efficacy by targeting multiple mechanisms of cancer progression, leading to improved tumor response rates and survival. When combination therapy utilizes a codelivery platform, it enables dose reduction of each agent, thereby reducing side effects and increasing the therapeutic index. The simultaneous delivery of two or more drugs and therapeutic agents to solid tumors remains a major challenge in the development of more effective treatments. Polymersomes, owing to their unique and bene

SUBMITTER: Mohammadi Zonouz A 

PROVIDER: S-EPMC12724104 | biostudies-literature | 2026 Dec

REPOSITORIES: biostudies-literature