Cancer and dementia incidence are strongly correlated worldwide: evidence from cross-national regression analyses.

ABSTRACT:

Background

Cancer and dementia are two major global health challenges influenced by population aging and socioeconomic transitions. Both impose substantial burdens, yet their relationship at the population level is insufficiently explored. This study investigated the global association between cancer incidence and dementia incidence, while accounting for developmental, demographic, and healthcare-related factors.

Methods

Data were obtained from the Institute for Health Metrics and Evaluation. Covariates included economic affluence, urbanization, reduced selection opportunity, and life expectancy e(60). Analyses across 204 countries employed correlations, partial correlations, principal component analysis, and multiple linear regression (enter and stepwise). Subgroup analyses

SUBMITTER: You W 

PROVIDER: S-EPMC12724431 | biostudies-literature | 2026 Dec

REPOSITORIES: biostudies-literature