Serial C-Reactive Protein Point-of-Care testing to optimize antibiotic treatment in hospitalized children with signs of infection in Zanzibar: A feasibility study.

ABSTRACT: Bacterial infections are among the leading causes of morbidity and mortality in children, especially in low- and middle- income countries. As a result, antibiotics are frequently prescribed to children with signs of infection, even when cause may not be bacterial. This contributes to antimicrobial resistance (AMR), a global health concern. Integrating serial CRP point-of-care testing with culture and susceptibility testing may improve decision-making by facilitating earlier differentiation between bacterial and non-bacterial infections, promoting more appropriate antibiotic use.The study examined the feasibility of serial CRP POCT to guide discontinuation of antibiotic treatment in children in selected hospitals in Zanzibar, and to determine barriers to methods and procedures for the upcom

SUBMITTER: Joshua D 

PROVIDER: S-EPMC12725598 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature