Sarcopenia and Cognitive Decline in Hospitalized Older Adults from a Prospective Study.

ABSTRACT: As populations age, sarcopenia increasingly impacts healthcare due to its associations with morbidity, mortality, and cognitive decline. This study is a cross-sectional analysis of prospectively collected data from 140 older adults hospitalized in an internal medicine department. Sarcopenia was measured by handgrip strength, and cognitive function by the Digit Symbol Substitution Test (DSST). Sarcopenic patients (n=78) had lower DSST scores (p=0.003) and Norton scores (p&;lt0.001) compared to non-sarcopenic patients. Handgrip strength showed a significant positive correlation with DSST scores (R=0.26, p=0.0019), persisting after adjustments for age and sex (R=0.42, p=1.7e-07). This study underscores a significant association between sarcopenia and cognitive decline in hospitalized older ad

SUBMITTER: Kon-Kfir S 

PROVIDER: S-EPMC12727076 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature