Intensive Surveillance and Aggressive Multimodal Treatment for Liver Metastases From Uveal Melanoma.

ABSTRACT:

Objective

We evaluated a cohort of patients with liver metastasis from uveal melanoma (LMUM) to assess the benefit of intensive surveillance and multimodal treatment on overall survival.

Background

LMUM is typically associated with a poor prognosis.

Patients and methods

This two-center retrospective cohort study from January 2010 to December 2024 included 58 patients with LMUM deemed to be oligometastatic and referred for surgical management. Overall survival after treatment of LMUM and primary uveal melanoma was determined using Kaplan-Meier methods and the Cox proportional hazards method.

Results

Fifty-eight patients [performance status (PS): PS1 = 11, PS0 = 47] with oligometastatic LMUM were screened to stratify patients with multifocal disease not undergoin

SUBMITTER: Kocher HM 

PROVIDER: S-EPMC12727333 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature