Suprasellar desmoplastic infantile astrocytoma and ganglioglioma: an institutional series report and a clinical summary of this rare tumor.

ABSTRACT:

Background

Desmoplastic infantile astrocytomas/ganglioglioma (DIA/DIG) arising in the suprasellar region are extremely rare, and their clinical features, optimal management, and outcomes remain unclear. We aimed to summarize the clinical manifestations, treatment strategies, and prognosis of this rare tumor entity.

Patients and methods

This retrospective case series included 5 institutional cases and 13 literature cases of suprasellar DIA/DIGs. The clinical and radiological characteristics, therapies, and outcomes of this rare tumor were examined.

Results

Our case series comprised 2 males and 3 females, with a median age of 6 months. Three patients underwent partial resection, and 2 had subtotal resection. During follow-up, the residual tumors in 2 patients showed spo

SUBMITTER: Wang Q 

PROVIDER: S-EPMC12727624 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature