Characteristics of pediatric interventional drug trials registered between 2015 and 2024 on ClinicalTrials.gov.

ABSTRACT:

Aim

This study comprehensively analyzed the characteristics and development trends of pediatric interventional drug clinical trials registered between 2015 and 2024, with a focus on pharmaceutical characteristics such as dosage form and administration route.

Methods

The ClinicalTrials.gov database was searched to identify trials involving pediatric participants. Interventional trials first posted between 2015 and 2024 were included if they used drugs as interventions and had treatment as the primary purpose.

Results

A total of 2,928 pediatric-only clinical trials were included, with annual registration numbers ranging from 257 to 339, exhibiting a declining trend. Among these, 1,975 (67.5%) enrolled no more than 100 participants, and 153 (5.2%) were restricted to eith

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC12727638 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature