In vivo imaging analyses to explore the integration of multimodal aversive sensory information in the central amygdala.

ABSTRACT: The negative emotions elicited by diverse aversive sensory stimuli induce avoidance behaviors and adaptive autonomic/hormonal responses, which are crucial for biological defense and homeostasis. The central amygdala (CeA), which receives a range of sensory information, plays important roles in stress and emotional responses. However, it remains unclear whether diverse sensory information from different sensory systems, such as the pain, olfactory, and gustatory systems, is received by the same group of CeA neurons and then integrated to generate negative emotions, or whether different neural pathways are used to generate negative emotions without converging on a specific group of CeA neurons. To clarify this issue, we conducted in vivo Ca²⁺ imaging to measure CeA neuron activity

SUBMITTER: Zhou X 

PROVIDER: S-EPMC12727694 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature