Prognostic value of endothelial activation and stress index in mechanical thrombectomy for patients with acute ischemic stroke.

ABSTRACT:

Background and purpose

The Endothelial Activation and Stress Index (EASIX) is a marker of endothelial dysfunction. This study aimed to explore the association between the EASIX score and unfavorable outcome in patients with acute ischemic stroke (AIS) undergoing mechanical thrombectomy (MT) treatment.

Methods

We enrolled AIS patients treated with MT from a multicenter study between June 2021 to September 2024. The EASIX score was calculated as lactate dehydrogenase (LDH) (U / L) × Creatinine (mg / dL) / Platelet Count (10 ^∧ 9 / L). The unfavorable outcome was defined as 90-day modified Rankin scale score 3-6. We used multivariable logistic regression models to investigate the association between EASIX score and unfavorable outcome. A restricted cubic spline analys

SUBMITTER: Zhu X 

PROVIDER: S-EPMC12727912 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature