Physical Activity, Telomere Length, and Cardiometabolic Syndrome in Older Women: The Cardiovascular Health Study.

ABSTRACT:

Background

Cardiometabolic syndrome (CMS) affects approximately 39% of US women and increases risk for cardiovascular disease, diabetes, and stroke. Telomere length, a biomarker of cellular aging, is associated with CMS and may be influenced by physical activity (PA), potentially mitigating telomere shortening. Black women have higher CMS prevalence compared to white women and may exhibit distinct telomere length dynamics influenced by interactions between CMS and PA.

Methods

Data were drawn from the Cardiovascular Health Study and included black and white women who provided data on PA, CMS risk factors, and telomere length (N = 417). Linear regression models examined the associations between CMS, PA, and telomere length cross-sectionally and prospectively, with analyses con

SUBMITTER: Page J 

PROVIDER: S-EPMC12728086 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature