The evolving etiologies of rapidly progressive dementia: a systematic review.

ABSTRACT:

Background and purpose

Rapidly progressive dementia (RPD) represents a heterogeneous group of clinical dementia syndromes characterized by a precipitous decline in cognitive function, typically occurring over weeks to months, with diverse underlying etiologies. To elucidate the evolving etiological spectrum of RPD and investigate temporal trends, we conducted a comprehensive systematic review incorporating temporal subgroup analyses.

Method

English-language studies published prior to December 31, 2024 were searched in the Medline (PubMed), ISI Web of Science and the Cochrane Library databases. Study design, study period, patient characteristics, etiologies of RPD in each study were retrieved.

Result

We encompassed 13 studies in our final systematic review, involving a

SUBMITTER: Lei MH 

PROVIDER: S-EPMC12728188 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature