A Minimalist Iron Porphyrin Which Can Catalyze Both Peroxidation and Oxygen Reduction Reaction.

ABSTRACT: Heme enzymes catalyze several key reactions in nature. O₂ reduction and peroxidation are two such reactions crucial for respiration and oxidation of organic and inorganic substrates in nature, respectively. Over the last several decades, there has been a focused effort to generate small-molecule analogues which mimic these reactions. Small-molecule mimics of these metallo-enzymes may find potential use as an oxygen reduction reaction (ORR) catalyst in a fuel cell and as a catalyst for decontamination of wastewater in addition to providing deeper insights into the reactivity of the enzyme they mimic. An iron porphyrin with a pendant imidazole group appears to catalyze both these reactions quite efficiently. On the one hand, the pendant imidazole group provides a binding site for

SUBMITTER: Dinda S 

PROVIDER: S-EPMC12728627 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature