Ag Nanoparticle Arrays for Highly Sensitive and Reliable Sulfide Detection.

ABSTRACT: Early disease diagnosis hinges on the sensitive detection of signaling molecules. Among them, hydrogen sulfide (H₂S) plays an important role in cardiovascular and neurological signal transduction. On-chip immunoanalysis, particularly interface detection based on nanoarrays, offers a highly promising avenue for ultrasensitive analysis due to its confined reaction volume and precise signal localization. This study introduces a Ag nanoparticle (NP) array for the sensitive detection of sulfide. The array applies the exceptional sensitivity of Ag to sulfide, where Ag reacts with S^2- to form Ag₂S, leading to a decrease in scattering intensity. The inherent parallel nature of the array with hundreds of independent reactions significantly enhances measurement relia

SUBMITTER: Pan J 

PROVIDER: S-EPMC12728747 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature