Association between multimorbidity and young-onset dementia: a prospective study.

ABSTRACT:

Background

Multimorbidity contributes to an increased risk of late-onset dementia, but the multimorbidity effect on young-onset dementia (YOD, defined as dementia diagnosed before age 65) remains unclear. We aimed to explore the associations between multimorbidity (including its burden, pattern, and trajectory) and YOD.

Methods

We utilized the China Health and Retirement Longitudinal Study in China. Multimorbidity burden, patterns and trajectories were assessed based on 12 chronic diseases from 2011 to 2015. Patterns of multimorbidity were analysed by hierarchical clustering in 2015. Group-based trajectory modeling (GBTM) was utilized to identify the trajectories of the number of newly developed chronic conditions from 2011 to 2015. YOD and probable YOD were assessed by self

SUBMITTER: Chen D 

PROVIDER: S-EPMC12729070 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature