Association between platelet-to-lymphocyte ratio and 28-day all-cause mortality in patients with asymptomatic coronary artery disease: a cohort study.

ABSTRACT:

Background

Recent evidence suggests a link between platelet-to-lymphocyte ratio (PLR) and coronary artery disease (CAD) outcomes. However, studies on asymptomatic CAD (ACAD) and short-term outcomes like 28-day mortality are limited. This research will explore the correlation between PLR and 28-day mortality in ACAD patients and assess a potential dose-response relationship.

Methods

This retrospective cohort study leverages data from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. We included patients diagnosed with ACAD and collected baseline characteristics, laboratory test results, and clinical data during hospitalization. The primary endpoint was 28-day all-cause mortality. Analytical approaches included multivariable Cox proportional hazards regre

SUBMITTER: Zhao J 

PROVIDER: S-EPMC12729227 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature