Etiologies of patients with adult-onset epilepsy over the past 25 years: a retrospective study in China.

ABSTRACT:

Objective

This study aimed to describe the changes in the etiology of adult epilepsy in different age groups over the past 25 years, with consideration of different time periods.

Methods

A retrospective study was conducted using the clinical data of patients with adult-onset epilepsy at The First Medical Center of Chinese PLA General Hospital between February 1999 and March 2024.

Results

The study included 5,712 patients from 25 provinces and 4 municipalities in China. The study found that the prevalence of unknown etiology has decreased overall, particularly after 2015, and that the proportion of epilepsy cases caused by metabolic etiologies has declined since 2016. However, since 2021, there has been an increase in immune-related epilepsy. The proportion of patients

SUBMITTER: Zhang X 

PROVIDER: S-EPMC12729239 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature