A Quality Improvement Bundle to Reduce Central Line-Associated Bloodstream Infections in Neonatal Intensive Care Unit: An Observational Study.

ABSTRACT: Background: Dedicated bundles were proven to reduce CLABSIs in a neonatal intensive care unit (NICU). Methods: We performed an observational pre-post study to evaluate the impact of a bundle for CLABSI prevention in our NICU. All umbilical vein catheters (UVCs) and epicutaneo-caval catheters (ECCs) with dwell time > 2 days were included. The primary outcome was CLABSI rate/1000 central line days. Results: A total of 145 catheters (67 UVCs and 78 ECCs) and 142 catheters (65 UVCs and 77 ECCs) were inserted before and after bundle implementation, respectively. The duration of the UVC was significantly shorter before than after the bundle [4 (3-6) vs. 8 (6-11) days; p < 0.0001], while the duration of the ECC did not differ [10 (6-17) vs. 11 (6-19) days; p = 0

SUBMITTER: Poggi C 

PROVIDER: S-EPMC12729402 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature