Genomic Characterization of NDM-1 Producer <i>Providencia stuartii</i> Isolated in Russia.

ABSTRACT: Background/Objectives:Providencia stuartii is intrinsically resistant to several antibiotic classes, and acquisition of bla_NDM further restricts treatment options. This study aimed to characterize NDM-producing P. stuartii isolates from a small hospital cluster in Russia and to place them within the global genomic context. Methods: Four isolates recovered between June and July 2023 from a single hospital were analyzed using Illumina and Oxford Nanopore sequencing to assess genetic relatedness and plasmid content. Results: The isolates showed identical extensively drug-resistant profiles and were closely related genomically. All carried nearly identical IncC plasmids harboring multiple antimicrobial resistance genes, including bla<

SUBMITTER: Shapovalova VV 

PROVIDER: S-EPMC12729570 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature