Expression dynamics of arsenic respiration and detoxification in Shewanella sp. strain ANA-3.

ABSTRACT: Because arsenate [As(V)] reduction by bacteria can significantly enhance arsenic mobility in the environment, it is important to be able to predict when this activity will occur. Currently, two bacterial systems are known that specifically reduce As(V), namely, a respiratory system (encoded by the arr genes) and a detoxification system (encoded by the ars genes). Here we analyze the conditions under which these two systems are expressed in Shewanella sp. strain ANA-3. The ars system is expressed under both aerobic and anaerobic conditions, whereas the arr system is only expressed anaerobically and is repressed by oxygen and nitrate. When cells are grown on As(V), the arr system is maximally induced during exponential growth, with peak expression of the ars system occurring at the beginning

SUBMITTER: Saltikov CW 

PROVIDER: S-EPMC1272973 | biostudies-literature | 2005 Nov

REPOSITORIES: biostudies-literature