Dataset Information
Systemic inflammation, polygenic risk score, and risk of incident abdominal aortic aneurysm in the UK biobank.
Ontology highlight
ABSTRACT:
SUBMITTER: Pu H
PROVIDER: S-EPMC12729862 | biostudies-literature | 2025 Dec
REPOSITORIES: biostudies-literature
Publications
Systemic inflammation, polygenic risk score, and risk of incident abdominal aortic aneurysm in the UK biobank.
BMC public health 20251224 1
AIMS: There remains clinical uncertainty concerning the relationship between systemic inflammation and subsequent abdominal aortic aneurysm (AAA) risk. To investigate the association between chronic systematic inflammation markers (C-reactive protein (CRP), peripheral immune cell counts, and their derived ratios) and risk of AAA incidence, and identify potential effect modifiers. METHODS: We included 271,068 individuals from the UK Biobank, who were free of aortic aneurysm and other conditions i ...[more]