Evaluation of Three Recombinant Antigens for the Detection of Anti-Coxiella Antibodies in Cattle.

ABSTRACT: Background/Objectives: The detection of anti-Coxiella antibodies using serological methods is essential for identifying exposed ruminants and preventing this important zoonotic disease in livestock. In recent years, numerous attempts have been made to increase diagnostic performance as well as simplify the production of serological assays. Commercially available tests often use whole-cell antigens, which can decrease specificity and require high-level biosafety facilities for manufacturing. The aim of this work was to produce three Coxiella burnetii (C. burnetii) antigens in recombinant form and assess them for the detection of anti-Coxiella antibodies in ruminants. Methods: Three recombinant C. burnetii antigens (Com-1, MceB, AdaA) were selected among im

SUBMITTER: Colitti B 

PROVIDER: S-EPMC12729987 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature