Lower Limb Biomechanical Outcomes Following Endoprosthetic Reconstruction for Distal Femur and Proximal Tibia Bone Tumors: A Systematic Review and Meta-Analysis.

ABSTRACT: Given the higher incidence of bone tumors in younger populations, achieving post-operative biomechanical stability is critical to maintaining long-term mobility. The objective of this study was to evaluate the biomechanical impact of endoprosthetic reconstruction in patients with distal femur and proximal tibia bone tumors in comparison with a control group. The Embase, Scopus, PubMed, and Cochrane databases were systematically searched until January 2025, according to PRISMA guidelines. Heterogeneity was assessed via Cochran's Q statistic and quantified using the I² statistic. A total of 23 studies with 692 participants were included, providing data on gait, knee muscle strength, energy expenditure during walking, physical activity level, balance, and joint position sense. Pati

SUBMITTER: Gao Y 

PROVIDER: S-EPMC12730080 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature