Transposable Elements Regulate Tail Development and Fat Deposition in Sheep Fetuses.

ABSTRACT: Transposable elements (TEs) play important roles in physiological processes, but their function in tail development remains poorly characterized. To explore their potential regulatory roles, we systematically analyzed the expression patterns of TEs during different fetal developmental stages of the sheep tail. Using RNA-seq data and the TEtranscripts pipeline, we identified differentially expressed TEs. Our key findings are as follows: (i) SINE/MIR, L1, and BovB elements exhibited significant stage-specific expression. (ii) The number of differentially expressed TEs was dynamic, with 2129 identified between stages E40-45 and E55-60, and 5554 between E55-60 and E70-75. (iii) These TEs were primarily located in intergenic regions, introns, and 3'UTRs, and their expression trends were highly

SUBMITTER: Liang Q 

PROVIDER: S-EPMC12730088 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature