Integrated Oxygen Consumption Rate, Energy Metabolism, and Transcriptome Analysis Reveal the Heat Sensitivity of Wild Amur Grayling (<i>Thymallus grubii</i>) Under Acute Warming.

ABSTRACT: Cold-water fish, particularly stenothermal species, are increasingly affected by rising temperatures driven by global warming. To explore the hepatic metabolism mode of Amur grayling under warming, Thymallus grubii was selected as the experimental model. Here, we measured the oxygen consumption rate (MO₂), energy metabolism enzymes, and transcription profiling in Thymallus grubii that was exposed to increased temperatures (9, 12, 15, 18, 21, and 24 °C) with the same flow velocity (34 cm/s). In this study, MO₂ initially increased and then decreased with rising temperature, with peak sensitivity between 12 and 15 °C (Q₁₀ = 5.30). Hemoglobin increased significantly at 12-18 °C but decreased in the 18-24 °C group (p < 0.05). Additionally, h

SUBMITTER: Zhai C 

PROVIDER: S-EPMC12730672 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature