Alveolar and Bronchial Nitric Oxide Parameters in Pre-Capillary Pulmonary Hypertension.

ABSTRACT: Background: Exhaled NO concentrations at different flow rates can be used to calculate pulmonary NO dynamics in the conductive and peripheral airways and can be described by the total bronchial flux of NO (JawNO) and alveolar NO concentration (CANO), respectively. Changes in these parameters have been shown in pre-capillary pulmonary hypertension (PH); however, data from studies with low sample sizes are controversial and did not prospectively assess JawNO and CANO after adequate therapy. Methods: Patients with untreated pre-capillary PH (group 1: N = 23, group 3: N = 11, group 4: N = 18) and control subjects (N = 27) were recruited in a single-center observational study. Patients with group 1 (N = 15) and group 4 PH (N = 13) also attended a single

SUBMITTER: Csoma B 

PROVIDER: S-EPMC12730688 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature