Systemic lupus erythematosus comorbid with chronic spontaneous urticaria: a multicentre retrospective study.

ABSTRACT:

Objectives

This retrospective study aims to characterise the epidemiological features of systemic lupus erythematosus (SLE) concomitant with chronic spontaneous urticaria (CSU), examines the correlation between CSU occurrence and lupus disease activity, and identifies comorbidity patterns and risk factors associated with SLE-CSU.

Methods

A total of 40 SLE patients with concomitant CSU and 160 age-matched and sex-matched SLE controls without CSU were included. The Mann-Whitney U-test was used to assess disease activity at SLE onset in both groups. A Wilcoxon signed-rank test was conducted to compare the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) scores before and after CSU onset in patients with SLE. χ² tests were applied to evaluate differences i

SUBMITTER: Zeng X 

PROVIDER: S-EPMC12730801 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature