Development and validation of a simple risk score model for predicting 3-year major adverse cardiovascular events in patients with coronary artery disease: a retrospective cohort study.

ABSTRACT:

Objectives

To develop and validate a simple risk score for predicting major adverse cardiovascular events (MACE) in coronary artery disease (CAD) patients using routinely available clinical variables.

Design

This was a cohort study with retrospective analysis of prospectively collected data.

Setting

This study was conducted at a tertiary care centre in China.

Participants

This cohort study included 7182 CAD patients, randomly divided into training dataset and testing dataset in a ratio of 3:1.

Primary and secondary outcome measures

The primary outcome was a composite of MACE (cardiovascular death, non-fatal MI, stroke and revascularisation). A Cox regression model was developed on a training set to identify independent predictors. Variables were assigned

SUBMITTER: Song M 

PROVIDER: S-EPMC12730824 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature