Post-Mastectomy Direct-to-Implant Pre-Pectoral Breast Reconstruction With Polyurethane-Coated Implants: A Systematic Review of Efficacy and Safety.

ABSTRACT: Pre-pectoral (PP) direct-to-implant (DTI) breast reconstruction has gained popularity as a muscle-sparing alternative to subpectoral techniques. Polyurethane-coated implants, with their unique mechanical and biological properties, may further optimize outcomes by reducing capsular contracture and improving implant stability. This systematic review aimed to evaluate the safety, efficacy, and patient-reported outcomes of post-mastectomy PP DTI breast reconstruction using polyurethane-coated implants. A systematic search of PubMed, Embase, Scopus, and Cochrane Library databases was conducted in accordance with PRISMA guidelines. Data on study design, patient and surgical characteristics, complications, aesthetic outcomes, and patient satisfaction were extracted. Risk of bias was assessed usin

SUBMITTER: Caimi E 

PROVIDER: S-EPMC12730869 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature