Association Between Periodontal Disease and Blood Biomarkers in U.S. Adults: A Cross-Sectional Study.

ABSTRACT: Background: Periodontal disease (PD) is a chronic inflammatory condition linked to systemic immunologic and metabolic alterations. This study evaluated associations between PD and three routinely measured blood biomarkers-white blood cell (WBC) count, serum albumin, and mean corpuscular hemoglobin concentration (MCHC)-using data from 4669 adults aged ≥30 years in the 2013-2014 National Health and Nutrition Examination Survey (NHANES). Methods: PD was defined dichotomously according to the Centers for Disease Control and Prevention/American Academy of Periodontology (CDC/AAP) surveillance criteria. All analyses incorporated NHANES sampling weights, strata, and primary sampling units. Weighted descriptive statistics compared characteristics by PD status. Stepwise survey-weighte

SUBMITTER: Alshammari D 

PROVIDER: S-EPMC12731155 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature